Glass panes adhesively-bonded to structural profiles allow for the design of stiff, structurally-redundant and transparent sandwich structures. In beam applications this is often achieved by bonding glass webs to glass fibre-reinforced polymer (GFRP) or steel flanges. However in glazing panel applications, e.g. vision panels of building envelopes, the need for transparency requires a swap in the position of these components: i.e. GFRP or steel core profiles are used to separate glass face sheets. Very limited research exists on the mechanical response of sandwich vision panels. The objective of this research is to study the shear and post-fracture responses of these panels. Four-point bending tests were performed on short-span GFRP-glass and steel-glass panels (with epoxy and acrylic joints respectively). In contrast to steel-glass panels, GFRP-glass panels failed first due to shear in the core. Post-fracture capacities of more than 50% of the maximum resisted load were achieved in all panels. Deformations at collapse were large due to the progressive failure of GFRP profiles and the plasticity of the acrylic adhesive. Numerical modelling and a new analytical tool are presented to evaluate the mechanical response of adhesively-bonded panels.