Increasing demands on security in an uncertain world have to be considered additionally by the building industry. Nowadays, large-sized glazing in the building envelope cannot disregard safety requirements. For this reason, laminated safety glass with a resistance against manual attack results in heavy and thick cross-sections. General attributes of security glazing can be optimised by using benefits of different materials. In this case, the lamination of thin glass with polycarbonate enables innovative composite panels with improved properties in contrast to common laminated safety glass. Two outer thin glass panes and one or more inner polycarbonate sheet laminated by thermoplastic interlayers define the cross-section. Nevertheless, thin glass-polycarbonate composite panels as a more efficient alternative to laminated safety glass as security glazing results in slighter cross-sections by achieving the highest resistance class P8B against manual attack. Several options for using annealed and chemically strengthened thin glass by laminating with polycarbonate are described as well as the results of the four-point bending test as setup for the structural behaviour. Thus, deformations and stresses of the bending tests are compared with numerical analyses to specify the capacity of shear connection. Finally, test results for a resistance against manual attack complete the study.